内容提要 Global developments in medicine and health shape trends in medical education. And in China education reform haecome an important focus as the country strives to meet the basic requirements for developing a medical education system that meets international standards. Significant medical developments abroad are now being incorporated into the education of both domestic and international-medical students in China, which includes students from the districts of China's Hong Kong, Macao and Taiwan that are taught through mandarin Chinese as well as students from a variety of other regions that are taught through the English language. This latter group creates higher demands for both schools and teachers. Unfortunately there is no consensus as to how to improve the level and quality of education for these students or even as to which English language materials should be used. Some teachers prefer to directly use original English language materials, while others make use of Chinese medical textbooks with the help of English language medical notes. The lack of consensus has emerged from the lack of English language medical textbookased on the characteristics of modern medical education in China. 目录 Chapter 1 Overview of Genetics1.1 Role of Genetics in Medicine1.2 Brief History1.3 Classification of Genetic Disorders1.4 Future of Medical GeneticsChapter 2 Molecular Basis of Heredity2.1 DNA Structure and Replication2.2 Organization of Human Genome2.3 Gene Expression2.4 Mutation and PolymorphismChapter 3 Chromosomal Basis of Heredity3.1 Characteristics of Human Chromatin and Chromosomes3.2 Sex Determination3.3 Variation in Chromosome Number3.4 Variation in Chromosome Structure3.5 Disorders of Autosomes and the Sex ChromosomeChapter 4 Single-gene Disorders4.1 Pedigree and Pedigree Analysis4.2 Autosomal Dominant Disease4.3 Autosomal Recessive Disease4.4 X-Iinked Dominant Genetic Disease4.5 X-1inked Recessive Genetic Disease4.6 Y-Iinked Genetic Disease4.7 Influencing Factors in the Analysis of Single-gene DisordersChapter 5 Mitochondrial Inherited Disorders5.1 Structure, Function and Inheritance of Mitochondria5.2 Mitochondrial DNA Mutations and Common Mitochondrial DiseasesChapter 6 Multifactorial Genetic Disorders6.1 Characteristics of Multifactorial Traits6.2 Inheritance of Multifactorial (Complex) Disorders6.3 Factors Affecting Estimation of Recurrence Risk for Multifactorial DisordersChapter 7 Human Biochemical Disorders7.1 Hemoglobinopathy7.2 Hemophilia7.3 Collagen Diseases7.4 Receptor Protein Disease7.5 Enzyme Protein DiseaseChapter 8 Population Genetics8.1 Population Genetic Equilibrium8.2 Factors Affecting Population Genetic Equilibrium8.3 Genetic LoadChapter 9 Tumor Genetics9.1 Chromosomal Aberration and Tumors9.2 Oncogene9.3 Tumor Suppressor Gene9.4 Genetic Mechanisms of Tumorigenesis9.5 Hereditary Malignant TumorsChapter 10 Diagnosis of Genetic Disorders10.1 Symptomatic Diagnosis10.2 Presymptomatic Diagnosis10.3 Prenatal DiagnosisChapter 11 Therapy of Hereditary Disease11.1 General Principles and Concerns11.2 Surgical, Pharmacological and Dietary Therapy11.3 Gene TherapyChapter 12 Prevention of Genetic Disorders12.1 Genetic Screening12.2 Genetic Counseling12.3 Genetic Register 作者介绍
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