现货 Extracellular Matrix In Development (Biology Of Extracellular Matrix) [9783642359347]

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作者Douglas W. DeSimone , Robert P. Mecham

出版社Springer Berlin Heidelberg

ISBN9783642359347

出版时间2013-03

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纸张其他

页数249页

正文语种英语

上书时间2023-03-07

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商品描述: Cells in the developing embryo depend on signals from the extracellular environment to help guide their differentiation. An important mediator in this process is the extracellular matrix - secreted macromolecules that interact to form large protein networks outside the cell. During development, the extracellular matrix serves to separate adjacent cell groups, participates in establishing morphogenic gradients, and, through its ability to interact directly will cell-surface receptors, provides developmental clocks and positional information. This volume discusses how the extracellular matrix influences fundamental developmental processes and how model systems can be used to elucidate ECM function. The topics addressed range from how ECM influences early development as well as repair processes in the adult that recapitulate developmental pathways.

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