间质性膀胱炎基础与临床9787523515976
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￥ 189.73 6.2折 ￥ 308 全新
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作者牛远杰韩瑞发 著
出版社科学技术文献出版社
ISBN9787523515976
出版时间2023-04
装帧精装
开本其他
定价308元
货号17599458
上书时间2024-12-21
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作者简介
"牛远杰，医学博士，美国罗彻斯特大学博士后，教授，博士生导师，国务院政府特特殊津贴专家，中组部“万人计划”领军人才，国家卫生计生突出贡献中青年专家，海河医学学者，杰出津门学者，首届天津名医。现任天津医科大学第二医院院长，天津市泌尿外科研究所所长，天津市泌尿外科基础医学重点实验室主任。 兼任中国医促会泌尿男性生殖医学分会主任委员，中华医学会泌尿外科学分会常务委员、基础研究学组组长，中国中西医结合学会泌尿外科专业委员会副主任委员，天津市医学会泌尿外科学分会主任委员，天津市中西医结合学会泌尿外科专业委员会名誉主任委员，《中华泌尿外科学杂志》等12本杂志编委。 韩瑞发，医学博士，美国哈佛大学博士后，二级教授，博士生导师，国务院政府特殊津贴专家，天津市政府授衔泌尿肿瘤生物治疗专家，原天津市泌尿外科研究所所长，天津市重点实验室主任，国家重点学科学术带头人。现任天津泌尿外科研究所泌尿肿瘤研究方向PI，天津医科大学第二医院泌尿肾病中心名誉主任。兼任中国中西医结合外科杂志常务编委，天津市中西医结合学会常务理事，中国中西医结合学会泌尿外科专业委员会名誉主任委员。 先后担任国家自然科学基金二审专家、国家科技进步奖、教育部技进步奖、中华医学科技奖评审专家，CUA委员，AUA、SBUR、EAU会员。曾荣获天津市“九五、十五”科技立功奖章，天津市劳动模范、天津市优秀教师、天津市优秀留学归国人员和中国中西医结合泌尿外科专业委员会终身成就奖。"
目录
"第一章 间质性膀胱炎认识与演变史 ···················································································1 第一节 间质性膀胱炎的认识起源 ················································································1 第二节 间质性膀胱炎的命名与演变 ·············································································3 第三节 间质性膀胱炎国际协作组织的起源与发展 ···························································7 第二章 间质性膀胱炎流行病学与症状患病率 ·····································································11 第一节 流行病学与相关研究 ····················································································11 第二节 间质性膀胱炎症状患病率 ··············································································13 第三节 工作效率与医疗保险利用率 ···········································································17 第三章 膀胱壁组织结构与相关生理学功能 ········································································19 第一节 膀胱黏膜上皮的结构与功能特点 ·····································································19 第二节 膀胱黏膜上皮的生理与生物学功能 ··································································21 第三节 膀胱平滑肌的结构与细胞生理功能 ··································································33 第四节 调控膀胱排尿功能的神经系统 ········································································38 第五节 调控膀胱排尿功能的化学信号、受体与传导通路 ················································44 第六节 间质性膀胱炎病理生理与膀胱功能的改变 ·························································56 第四章 肥大细胞与间质性膀胱炎 ····················································································78 第一节 概述 ·········································································································78 第二节 肥大细胞的起源与迁移 ·················································································79 第三节 肥大细胞的表型与分布 ·················································································81 第四节 肥大细胞的发育与成熟 ·················································································82 第五节 肥大细胞的激活与脱颗粒 ··············································································83 第六节 肥大细胞与间质性膀胱炎的相关证据 ·······························································87 第五章 膀胱黏膜上皮损伤与间质性膀胱炎 ········································································91 第一节 概述 ·········································································································91 第二节 黏膜组织结构与细胞生物学功能 ·····································································92 第三节 间质性膀胱炎黏膜损伤与病理组织学证据 ·························································95 第四节 结语 ·········································································································99 第六章 雌激素与间质性膀胱炎 ······················································································102 第一节 概述 ········································································································102 第二节 雌激素-受体与膀胱上皮细胞 ·······································································105 第三节 雌激素与肥大细胞雌激素受体 ·······································································106 第四节 雌激素水平变化与间质性膀胱炎症状的相关性 ··················································107 第五节 雌激素阻断剂治疗间质性膀胱炎作用与评价 ·····················································108 第六节 结语 ········································································································109 第七章 获得性免疫与间质性膀胱炎 ················································································112 第一节 获得性免疫的概念 ······················································································112 第二节 获得性免疫的构成与功能 ·············································································113 第三节 获得性免疫反应与间质性膀胱炎 ····································································119 第四节 间质性膀胱炎膀胱挛缩的病因机制 ·································································121 第八章 神经生物学与间质性膀胱炎疼痛机制 ····································································126 第一节 概述 ········································································································126 第二节 神经源性炎症与膀胱疼痛 ·············································································129 第三节 间质性膀胱炎膀胱疼痛与周围神经敏化 ···························································131 第四节 间质性膀胱炎膀胱疼痛与中枢神经敏化 ···························································132 第九章 间质性膀胱炎诊断与鉴别诊断方法 ·······································································135 第一节 概述 ········································································································135 第二节 临床表现与症状特点 ···················································································136 第三节 IC症状评分系统与评价 ················································································137 第四节 实验室检查与尿液分析 ················································································143 第十章 间质性膀胱炎与尿液相关分子标志物 ····································································147 第一节 概述 ········································································································147 第二节 间质性膀胱炎与白细胞介素 ··········································································149 第三节 趋化因子表达与间质性膀胱炎 ·······································································152 第四节 血管内皮生长因子表达与间质性膀胱炎 ···························································153 第五节 肿瘤坏死因子与间质性膀胱炎 ·······································································156 第六节 神经生长因子与间质性膀胱炎疼痛机制 ···························································158 第七节 类胰蛋白酶与间质性膀胱炎 ··········································································163 第八节 糖胺聚糖与间质性膀胱炎 ·············································································166 第九节 问题与展望 ·······························································································168 第十一章 间质性膀胱炎尿流动力学表现与鉴别疾病 ···························································170 第一节 概述 ········································································································170 第二节 尿流动力学原理与方法 ················································································171 第三节 间质性膀胱炎尿流动力学表现 ·······································································179 第四节 尿流动力学用于间质性膀胱炎的鉴别诊断 ························································181 第五节 结语 ········································································································182 第十二章 超声在间质性膀胱炎诊断中的应用 ····································································184 第一节 概述 ········································································································184 第二节 正常膀胱壁的超声表现 ················································································185 第三节 间质性膀胱炎的超声表现 ·············································································187 第四节 超声对间质性膀胱炎相关疾病的鉴别诊断 ························································188 第五节 问题与展望 ·······························································································191 第十三章 成像技术与间质性膀胱炎 ················································································193 第一节 概述 ········································································································193 第二节 成像技术基本原理与应用 ·············································································194 第三节 磁共振成像技术原理与进展 ··········································································195 第四节 正常膀胱壁磁共振成像与结构特点 ·································································197 第五节 间质性膀胱炎磁共振成像与结构改变 ······························································198 第六节 磁共振功能成像对间质性膀胱炎疼痛的中枢定位研究 ·········································200 第十四章 间质性膀胱炎诊断指南与评价 ··········································································203 第一节 欧洲泌尿外科学会间质性膀胱炎诊断指南与评价 ···············································203 第二节 美国泌尿外科学会间质性膀胱炎诊断指南与评价 ···············································205 第三节 加拿大泌尿外科学会间质性膀胱炎诊断指南与评价 ············································207 第十五章 男性间质性膀胱炎的认识与诊疗原则 ·································································214 第一节 概述 ········································································································214 第二节 流行病学与发病率 ······················································································214 第三节 病因与病理 ·······························································································215 第四节 诊断与鉴别诊断 ·························································································216 第五节 间质性
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