Blood-brain Barriers: From Ontogeny to Artificial Interfaces, 血脑屏障第 1 卷

78 九五品

仅1件

辽宁抚顺

认证卖家担保交易快速发货售后保障

作者Prof. Dr. Rolf Dermietzel, Prof. Dr. David C. Spray, Prof. Dr. Maiken Nedergaard

出版社Wiley-VCH

ISBN9783527310883

出版时间2006-01

版次1

出版地德国

印刷时间2006-01

印次1

装帧精装

纸张铜版纸

页数428页

上书时间2018-06-10

已实名进店收藏店铺

商品描述: This first handbook to integrate developmental and cellular aspects combines the different structural and functional features involved in the regulation of brain perfusion and neuronal function. It highlights pharmacological and biomedical applications with sections on drug delivery and disease-related states as well as explaining in detail the role of astrocytes, shown to be an essential link between neurons and cerebral blood vessels. In addition the book studies how the structural elements interact in response to the dynamics of neuronal activities, necessitating adaptive mechanism of the interface. A significant part of the book describes new approaches to how the barrier can be surmised for drug delivery and how it can be mimicked by artificial in vitro systems for drug testing. Finally, the involvement of the barrier in brain diseases is considered, focusing on inflammatory and neurodegenerative disorders of the brain.
Covering basic knowledge as well as specific information dealing with very recent progress in blood-brain interface research, this book will be of interest to a broad audience.