Design of Controlled Release Drug Delivery Systems (McGraw-Hill Chemical Engineering)

图书标准信息

• 作者 Xiaoling Li 著
• 出版社 McGraw-Hill Professional
• 出版时间 2005-11
• 版次 1
• ISBN 9780071417594
• 定价 1446.70元
• 装帧 精装
• 开本 其他
• 纸张 其他
• 页数 435页
• 正文语种 英语

【内容简介】

Thisisarigorousexplorationofthestateoftheartincontrolledreleasedrugdelivery.WrittenbyanInternationalteamofexperts,thiscomprehensivetextofferspharmaceuticalscientistsandengineersworkinginthefield,state-of-the-artdesignprinciplesforthedevelopmentandbioengineeringofdrugdeliverysystems/technology.Readerswillfinddrugdeliverysystemspresentedwithaparticularemphasisonthedesignprinciplesandtheirphysiological/pathologicalbasis.Foreachspecificdesignprinciple,thecontributorsbrieflyintroducetherelevantpharmacokinetics(wherenecessary)andincludethechallengesofdifferentbiologicalbarriersthatneedtobeovercome.Thisin-depthtextfeaturesdetailedcoverageof:physiologicalandbiochemicalbarrierstodrugdelivery;pharmacokineticsandpharmacodynamicsofdrugdelivery;diffusionanddissolutionstrategies;rodrugsBioadhesiveandgastricretentivesystems;physiologicalandbiochemicalbarrierstodrugdelivery;targeteddrugdelivery;devicecontrolledandprogrammabledrugdelivery;and,more.Acomprehensivereferenceonthebiochemical,physical,andtechnicalaspectsofdrugdeliverysystems,thistitleincludes:;PharmacokineticsandPharmacodynamics-ApplicationsintheDesignofControlledReleaseDrugDeliverySystems;BarrierstoDrugDelivery:PhysiologicalandBiochemicalAspects;ProdrugsasDeliverySystems;DiffusionControlledSystems;DissolutionControlledSystems;OsmoticControlledSystems;BiodegradablePolymericDeliverySystems;GastricRetentionRetentiveDosageForms;DeviceControlledDeliveryofPowders;PhysicalTargetingofApproachesforDrugDelivery;LigandBasedDrugTargetingApproachesforDrugDelivery;ProgrammableDrugDeliverySystems;and,CarrierandVectorMediatedDeliverySystemsforBiologicalMacromolecules.

【作者简介】

XiaolingLi,Ph.D.,isaProfessorandChairoftheDepartmentofPharmaceuticsandMedicinalChemistry,ThomasJ.LongSchoolofPharmacy&HealthSciences,UniversityofthePacific,Stockton,California.ProfessorLireceivedhisPh.D.degreefromtheUniversityofUtahandhadhispostdoctoraltrainingatCiba-Geigy(nowNovartis).Hisresearchinterestsarefocusedondesignandsynthesisofnovelpolymersforpharmaceuticalandbiomedicalapplications,targeteddrugdelivery,andtransportofdrugacrossbiologicalbarriers.Heholdstwopatents,published38papers,andhadmorethan70presentationsatnationalandinternationalconferences.Heservesasaconsultantforvariouspharmaceuticalandbiotechnologycompanies.BhaskaraR.Jasti,Ph.D.isanAssociateProfessorintheDepartmentofPharmaceuticsandMedicinalChemistry,ThomasJ.LongSchoolofPharmacy&HealthSciences,UniversityofthePacific,Stockton,California.PriortojoiningtheUniversityofthePacific,heworkedasaStaffScientistatCygnusTherapeuticsSystems,anAssistantProfessoratWayneStateUniversityintheDepartmentsofPharmacyandInternalMedicine,wherehealsoactedasanAssistantDirectorofpharmacologycore.Hiscurrentresearchinterestsareidentifyingbarriersfordrugdeliveryandthedesignoftargetedandmucosaldrugdeliverysystems.Dr.Jastihaspublishedmorethan50papersatvariousnationalandinternationalmeetings.