Antibody-based therapeutics contribute to an ever-increasing share of successful pharmaceuticals. The objective of this volume is to provide a series of guides to those evaluating and preparing to enter particular areas within the field. The chapters set into context the significance of key developments and important considerations for selecting different approaches, such as antibody humanization, isotype selection, lead candidate selection criteria and protein production. Despite the wide use of antibodies as tools, antibody drug discovery technologies are isolated to a limited number of centers of excellence in industry and academia. All contributors are experts in their fields and have played pivotal roles in the creation of these technologies. Key Features ? A single volume that covers all major technology dimensions for antibody drug discovery ? Contributors are leading experts who have played pivotal roles in creating antibody technology and are actively using it to make decisions in this area ? A “points to consider” based approach that provides guidance in critically evaluating different technology options for the antibody drug discovery professional
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