现货 Maternal Fetal Transmission of Human Viruses and Their Influence on Tumorigenesis (2012)[9789400742154]

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上海宝山

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作者Berencsi III, Gy?rgy

出版社Springer

ISBN9789400742154

出版时间2012-04

装帧精装

纸张其他

页数464页

正文语种英语

上书时间2023-04-11

已实名已认证进店收藏店铺

商品描述: The human foetus is separated from the maternal blood by the syncytiotrophoblast induced by endogeneous human retrovirus-encoded proteins. This barrier is a highly developed one, which suppors apical-basolateral transport of maternal idiotype and anti-idiotype IgG, IgG-virus complexes. The selective maternal-fetal transport of epitope- and paratope-bearing entities can influence the developping fetal immune system during pregnancy. The bidirectional maternal-fetal transfer of cells are of even more importance during pregnancy. Maternal cells with latent viruses transport viruses without impairment of fetal development. Cells with premaligant and malignant genetic transformation are also transported to the fetus. Fetal and neonatal tumours are initiated by such cells in spite of the antitumour potential of fetal organism. On the contary, the fetal cells repair maternal tissue injouries and survive in the organisms of the recipients for decades. These possess new consequences for the neonatal immunity and organ transplatation surgery.

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