消息首页搜索举报

现货 Heat Shock Factor [9784431558507]

1427 九五品

仅1件

上海宝山

认证卖家担保交易快速发货售后保障

作者Akira Nakai

出版社Springer Japan

ISBN9784431558507

出版时间2016-01

装帧精装

纸张其他

页数283页

正文语种英语

上书时间2023-03-07

环球外文图书专营店

已实名已认证进店收藏店铺

在售商品暂无
平均发货时间 58小时
好评率暂无

最新上架

How to Win the War on Truth : An Illustrated Guide to How Mistruths Are Sold, Why They Stick, and How to Reclaim Reality [9781683693086] ¥180.00

现货Was Socialist Realism Global?: Modernism, Soc-Modernism, Socially Engaged Figuration Volume 21[9788393381838] ¥240.00

现货Singaporean Creatures: Histories of Humans and Other Animals in the Garden City[9789813252387] ¥293.00

现货Agricultural Knowledge Networks in Rural Europe, 1700-2000[9781783277124] ¥853.00

现货Cultural Legacies of Old Norse Literature: New Perspectives[9781843846383] ¥853.00

现货Visible!: Attracting Customers in a Distracted World[9783593517117] ¥225.00

现货Giorgio Vasari: The Man and the Book[9780691252216] ¥361.00

现货Nudibranchs of Britain, Ireland and Northwest Europe: Second Edition[9780691208794] ¥323.00

现货A Precarious Happiness: Adorno and the Sources of Normativity[9780226828572] ¥323.00

商品详情

品相描述：九五品

商品描述: This book presents a large amount of information related to the heat shock response and heat shock factor (HSF), describes core observations about molecular mechanisms and pathophysiological roles, and provides fundamental concepts on the basis of information from diverse aspects. This adaptive response to high temperature or protein misfolding is a fundamental mechanism to maintain the capacity of protein homeostasis, or proteostasis, and is evolutionally conserved among all living organisms, including bacteria and humans, on the earth. Furthermore, physiological and pathological roles of HSF have been extensively studied in fruit fly, worm, and mouse models. It has been revealed that HSF plays roles in development of the brain, reproductive and sensory organs, and in ageing, inflammation, and circadian rhythm. Analysis of the mechanisms have uncovered that HSF exerts a wide range of effects on gene expression and epigenetic status on the whole genome. Moreover, loss or gain of HSF function is also closely related to protein-misfolding diseases including neurodegenerative diseases, psychiatric diseases, heart diseases, and cancers. Therefore, HSF is now thought to be a promising therapeutic target for treatment of these refractory diseases.For undergraduate students, this is a highly understandable source of information on heart shock response and HSF, covering the basis of HSF biology, the physiological role of HSF, and disease associated with HSF function. This book not only serves as a guide to the heat shock response and HSF for students and young researchers in other fields, but also is a cornerstone for future work in the field related to the heat shock response and HSF.

— 没有更多了 —