内容提要 本书分为九章,包括化学基础知识、微生物、生物化学、发酵工程、酶工程、制药工程、药物制剂及GMP等,每章包括阅读材料、词汇、联系和参考译文。内容上覆盖生物和制药的基本领域,同时突出行业发展方向。 目录 Unit 1 Chemical Basic KnowledgeChapter 1 Atoms and Molecules1. Elements and compounds2. Chemical reactions and physical changes3. Atoms and moleculesChapter 2 Organic Compounds1. What is an organic compound?2. Kinds of organic compounds3. The saturated hydrocarbons, or Alkanes4. StructureUnit 2 BiochemistryChapter 1 Chemical Elements of Life1. The origin of life2. The chemical elements of lifeChapter 2 Biomolecules: Carbohydrates, Lipids and Protein1. Many important macromolecules are polymers2. Carbohydrates3. Lipids4. Protein5. Nucleic acidChapter 3 Glycolysis1. Glycolysis pathway in many organisms2. The citric acid cycleChapter 4 Diabetes and Human Health1. What is diabetes mellitus?2. What causes diabetes?3. Diabetes diagnosis4. Regulation of glucose transporter translocator in health and diabetesUnit 3 MicrobiologyChapter 1 Introduction of Microbiology1. The discovery of microorganisms2. The relationship between microorganisms and diseases3. The development of techniques for studying microbial pathogens4. Members of the microbial worldChapter 2 Microorganism and Culture Media1. The common nutrient requirements2. Nutritional types of microorganisms3. Uptake of nutrients by the cell4. Culture mediaChapter 3 Microbial Growth1. The Growth curve2. The Continuous culture of microorganismsChapter 4 Recent Developments in the Production of Valuable Microbial ProductsUnit 4 Fermentation EngineeringChapter 1 Fermentation Microbiology and Biotechnology1. The nature of fermentation2. Chemical and biological engineeringChapter 2 Strain Screen1. Selection and screening2. MutagenesisChapter 3 Fermentation Medium1. Fermentation medium2. Growth mediumChapter 4 Fermentation Engineering1. Fermenters2. Other fermenter design and ancillary equipmentChapter 5 Production of Antibiotics1. Antibiotics2. PenicillinsUnit 5 EnzymeChapter 1 The Biological Catalysts of Life1. Introduction2. Classi.cation and nomenclature of enzyme3. Enzyme applicationsChapter 2 Enzyme Production1. Summary2. Enzyme sources3. Strain development4. Growth requirements of microorganisms5. Fermentation6. Regulations during enzyme productionChapter 3 Immobilized Enzyme Technology1. Immobilization techniques2. Bene.ts and characteristicsUnit 6 Production of Dosage FormsChapter 1 Introduction to Drugs1. What is a drug?2. Drug bioavailabilityChapter 2 Oral Preparation1. Dosage forms application2. AbsorptionChapter 3 Parenteral Administration1. Introduction2. Routes of parenteral administration3. The preparation of parenteral productsChapter 4 Drug for External Use1. Epicutaneous route2. Ocular, otic, and nasal routesUnit 7 Good Manufacturing Practice for DrugsChapter 1 Process Validation:General Principles and Practics1. General considerations for process validation2. Stage 1——process design3. Stage 2——process quali.cation4. Stage 3——continued process veri.cationChapter 2 Non-Penicillin β-Lactam Drugs: A CGMP Framework for Preventing Cross-Contamination1. Regulatory framework2.β-lactam antibiotics3.β-lactamase inhibitors4.β-lactam intermediates and derivatives 作者介绍 汤卫华,女,36岁,副教授,任职于天津现代职业技术学院。主要作品:《发酵过程控制技术》《氨基酸发酵生产技术》。 序言
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