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间质性膀胱炎基础与临床 9787523515976

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作者牛远杰韩瑞发 著

出版社科学技术文献出版社

ISBN9787523515976

出版时间2024-09

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定价308元

货号1203371580

上书时间2024-09-17

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作者简介
"牛远杰，医学博士，美国罗彻斯特大学博士后，教授，博士生导师，国务院政府特特殊津贴专家，中组部“万人计划”领军人才，国家卫生计生突出贡献中青年专家，海河医学学者，杰出津门学者，首届天津名医。现任天津医科大学第二医院院长，天津市泌尿外科研究所所长，天津市泌尿外科基础医学重点实验室主任。
兼任中国医促会泌尿男性生殖医学分会主任委员，中华医学会泌尿外科学分会常务委员、基础研究学组组长，中国中西医结合学会泌尿外科专业委员会副主任委员，天津市医学会泌尿外科学分会主任委员，天津市中西医结合学会泌尿外科专业委员会名誉主任委员，《中华泌尿外科学杂志》等12本杂志编委。
韩瑞发，医学博士，美国哈佛大学博士后，二级教授，博士生导师，国务院政府特殊津贴专家，天津市政府授衔泌尿肿瘤生物治疗专家，原天津市泌尿外科研究所所长，天津市重点实验室主任，国家重点学科学术带头人。现任天津泌尿外科研究所泌尿肿瘤研究方向PI，天津医科大学第二医院泌尿肾病中心名誉主任。兼任中国中西医结合外科杂志常务编委，天津市中西医结合学会常务理事，中国中西医结合学会泌尿外科专业委员会名誉主任委员。
先后担任国家自然科学基金二审专家、国家科技进步奖、教育部技进步奖、中华医学科技奖评审专家，CUA委员，AUA、SBUR、EAU会员。曾荣获天津市“九五、十五”科技立功奖章，天津市劳动模范、天津市优秀教师、天津市优秀留学归国人员和中国中西医结合泌尿外科专业委员会终身成就奖。"

目录
"第一章  间质性膀胱炎认识与演变史 ···················································································1
第一节  间质性膀胱炎的认识起源 ················································································1
第二节  间质性膀胱炎的命名与演变 ·············································································3
第三节  间质性膀胱炎国际协作组织的起源与发展 ···························································7
第二章  间质性膀胱炎流行病学与症状患病率 ·····································································11
第一节  流行病学与相关研究 ····················································································11
第二节  间质性膀胱炎症状患病率 ··············································································13
第三节  工作效率与医疗保险利用率 ···········································································17
第三章  膀胱壁组织结构与相关生理学功能 ········································································19
第一节  膀胱黏膜上皮的结构与功能特点 ·····································································19
第二节  膀胱黏膜上皮的生理与生物学功能 ··································································21
第三节  膀胱平滑肌的结构与细胞生理功能 ··································································33
第四节  调控膀胱排尿功能的神经系统 ········································································38
第五节  调控膀胱排尿功能的化学信号、受体与传导通路 ················································44
第六节  间质性膀胱炎病理生理与膀胱功能的改变 ·························································56
第四章  肥大细胞与间质性膀胱炎 ····················································································78
第一节  概述 ·········································································································78
第二节  肥大细胞的起源与迁移 ·················································································79
第三节  肥大细胞的表型与分布 ·················································································81
第四节  肥大细胞的发育与成熟 ·················································································82
第五节  肥大细胞的激活与脱颗粒 ··············································································83
第六节  肥大细胞与间质性膀胱炎的相关证据 ·······························································87
第五章  膀胱黏膜上皮损伤与间质性膀胱炎 ········································································91
第一节  概述 ·········································································································91
第二节  黏膜组织结构与细胞生物学功能 ·····································································92
第三节  间质性膀胱炎黏膜损伤与病理组织学证据 ·························································95
第四节  结语 ·········································································································99
第六章  雌激素与间质性膀胱炎 ······················································································102
第一节  概述 ········································································································102
第二节  雌激素-受体与膀胱上皮细胞 ·······································································105
第三节  雌激素与肥大细胞雌激素受体 ·······································································106
第四节  雌激素水平变化与间质性膀胱炎症状的相关性 ··················································107
第五节  雌激素阻断剂治疗间质性膀胱炎作用与评价 ·····················································108
第六节  结语 ········································································································109
第七章  获得性免疫与间质性膀胱炎 ················································································112
第一节  获得性免疫的概念 ······················································································112
第二节  获得性免疫的构成与功能 ·············································································113
第三节  获得性免疫反应与间质性膀胱炎 ····································································119
第四节  间质性膀胱炎膀胱挛缩的病因机制 ·································································121
第八章  神经生物学与间质性膀胱炎疼痛机制 ····································································126
第一节  概述 ········································································································126
第二节  神经源性炎症与膀胱疼痛 ·············································································129
第三节  间质性膀胱炎膀胱疼痛与周围神经敏化 ···························································131
第四节  间质性膀胱炎膀胱疼痛与中枢神经敏化 ···························································132
第九章  间质性膀胱炎诊断与鉴别诊断方法 ·······································································135
第一节  概述 ········································································································135
第二节  临床表现与症状特点 ···················································································136
第三节  IC症状评分系统与评价 ················································································137
第四节  实验室检查与尿液分析 ················································································143
第十章  间质性膀胱炎与尿液相关分子标志物 ····································································147
第一节  概述 ········································································································147
第二节  间质性膀胱炎与白细胞介素 ··········································································149
第三节  趋化因子表达与间质性膀胱炎 ·······································································152
第四节  血管内皮生长因子表达与间质性膀胱炎 ···························································153
第五节  肿瘤坏死因子与间质性膀胱炎 ·······································································156
第六节  神经生长因子与间质性膀胱炎疼痛机制 ···························································158
第七节  类胰蛋白酶与间质性膀胱炎 ··········································································163
第八节  糖胺聚糖与间质性膀胱炎 ·············································································166
第九节  问题与展望 ·······························································································168
第十一章  间质性膀胱炎尿流动力学表现与鉴别疾病 ···························································170
第一节  概述 ········································································································170
第二节  尿流动力学原理与方法 ················································································171
第三节  间质性膀胱炎尿流动力学表现 ·······································································179
第四节  尿流动力学用于间质性膀胱炎的鉴别诊断 ························································181
第五节  结语 ········································································································182
第十二章  超声在间质性膀胱炎诊断中的应用 ····································································184
第一节  概述 ········································································································184
第二节  正常膀胱壁的超声表现 ················································································185
第三节  间质性膀胱炎的超声表现 ·············································································187
第四节  超声对间质性膀胱炎相关疾病的鉴别诊断 ························································188
第五节  问题与展望 ·······························································································191
第十三章  成像技术与间质性膀胱炎 ················································································193
第一节  概述 ········································································································193
第二节  成像技术基本原理与应用 ·············································································194
第三节  磁共振成像技术原理与进展 ··········································································195
第四节  正常膀胱壁磁共振成像与结构特点 ·································································197
第五节  间质性膀胱炎磁共振成像与结构改变 ······························································198
第六节  磁共振功能成像对间质性膀胱炎疼痛的中枢定位研究 ·········································200
第十四章  间质性膀胱炎诊断指南与评价 ··········································································203
第一节  欧洲泌尿外科学会间质性膀胱炎诊断指南与评价 ···············································203
第二节  美国泌尿外科学会间质性膀胱炎诊断指南与评价 ···············································205
第三节  加拿大泌尿外科学会间质性膀胱炎诊断指南与评价 ············································207
第十五章  男性间质性膀胱炎的认识与诊疗原则 ·································································214
第一节  概述 ········································································································214
第二节  流行病学与发病率 ······················································································214
第三节  病因与病理 ·······························································································215
第四节  诊断与鉴别诊断 ······················

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