【编辑推荐】: 本书为英文版,系统介绍了人工肾的起源、结构系统、工作原理及发展前景,详细论述了多种人工肾数理模型和计算机模拟优化方法,并运用大量实例阐述了人工肾实验研究方法。 全书包括了Introduction、Numerical Analyses of Mass Transfer in Artificial Kidney、In Vitro Experimental Study of Hemodialysis等六个部分的内容。
【目录】: Preface to the USTC Alumni's Series List of Symbols Section Ⅰ Introduction Chapter 1 Human Kidneys 1.1 Function and Structure of Human Kidney 1.2 Kidney Failure 1.3 End-Stage Renal Disease 1.4 Classification of Uremic Solutes Chapter 2 Artificial Kidneys 2.1 Function and Structure of Artificial Kidney 2.2 Major Milestones of Artificial Kidney Development 2.3 Classification of Artificial Kidneys 2.4 Dialysis Membranes Chapter 3 Transport in Artificial Kidneys 3.1 Diffusive Transport 3.2 Convective Transport 3.3 Coupled Diffusive-Convective Transport References Section Ⅱ Numerical Analyses of Mass Transfer in Artificial Kidney Chapter 4 Equivalent Annulus Model 4.1 Introduction 4.2 Modeling 4.3 Numerical Algorithm 4.4 Results and Discussion 4.5 Conclusions Chapter 5 Porous Media Model 5.1 Introduction 5.2 Modeling and Algorithm 5.3 Results and Discussion 5.4 Conclusions Chapter 6 Double Porous Media Model 6.1 Introduction 6.2 Theory 6.3 Simulation Conditions 6.4 Validation of Model 6.5 Conclusions Chapter 7 Determinations of Membrane Properties and Parameters 7.1 Introduction 7.2 Preparation of Mini-Module Dialyzer 7.3 Selection of Solutes 7.4 Measurement of Hydraulic Permeability 7.5 Measurement of Diffusive Permeability 7.6 Measurement of Reflection Coefficient 7.7 Sample Assays 7.8 Calculation of Pore Size 7.9 Measurement of Darcy Permeability Chapter 8 Kinetic Modeling in Hemodialysis 8.1 Introduction 8.2 Simulation of Continuous Renal Replacement Therapy(CRRT) 8.3 Intermittent Hemodialysis and Sustained Low-EfficiencyDialysis 8.4 Results and Discussion 8.5 Conclusions References Section Ⅲ In Vitro Experimental Study of Hemodialysis Chapter 9 Introduction to General in Vitro Methodologies 9.1 Hemodialyzers and Hemofilters 9.2 Experimental Solutes 9.3 System Setup 9.4 Data Analysis Chapter 10 Local Clearance of Hemodialyzer 10.1 Introduction 10.2 Materials and Methods 10.3 Experiment Setup 10.4 Data Collection and Analysis 10.5 Results and Discussion 10.6 Conclusions Chapter 11 Effects of Dialyzer Reprocessing 11.1 Introduction 11.2 Materials and Methods 11.3 Results and Discussion 11.4 Conclusions Chapter 12 Cytokine-Induced Substance Back Transport in a High Flux Dialyzer 12.1 Introduction 12.2 Materials and Methods 12.3 Results 12.4 Discussion 12.5 Conclusions Chapter 13 A Study of Dilution Mode and Ultrafiltration Rate in a High Volume Continuous Hemofiltration 13.1 Introduction 13.2 Materials and Methods 13.3 Assays 13.4 Results 13.5 Conclusions Chapter 14 Determinants of Solute Clearance in Hemodiafiltration 14.1 Introduction 14.2 Purpose 14.3 Materials and Methods 14.4 Assays 14.5 Results and Discussion 14.6 Conclusions References Section Ⅳ Novel MRI Approach for Flow Field Measurement Chapter 15 Basic Principles of MRI 15.1 Magnetic Properties of Atomic Nuclei 15.2 Relaxation Processes 15.3 Standard Imaging Pulse Sequences 15.4 Magnetic Resonance Flow-Imaging Techniques Chapter 16 Experimental Design and Image Analysis 16.1 Flow Phantom 16.2 2-D Phase-Contrast Study 16.3 2-D Fourier-Transform Study 16.4 Results of 2-D Phase-Contrast Study 16.5 Results of 2-D Fourier-Transform Study References Section Ⅴ Advances in New Membrane Development Chapter 17 Ceramic Membrane for Hemodialysis 17.1 Introduction 17.2 Principle of Aluminum Anodization 17.3 Materials and Methods 17.4 Results and Discussion 17.5 Conclusions Chapter 18 Bio-functional Artificial Kidney 18.1 Current Status of Therapy for Renal Failure 18.2 Bioengineered Kidney References
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