经典英文化学教材系列：有机合成现代方法（第4版）

图书标准信息

• 作者 [英]卡如萨 著
• 出版社 世界图书出版公司
• 出版时间 2008-10
• 版次 1
• ISBN 9787506292702
• 定价 99.00元
• 装帧 平装
• 开本 16开
• 纸张 胶版纸
• 页数 493页
• 正文语种 简体中文，英语

【内容简介】

　　Thefourtheditionofthiswell-knowntextbookdiscussesthekeymethodsusedinorganicsynthesis,showingthevalueandscopeofthesemethodsandhowtheyareusedinthesynthesisofcomplexmolecules.Allthetextfromthethirdeditionhasbeenrevised,toproduceamodemaccountoftraditionalmethodsandanup-to-datedescriptionofrecentadvancementsinsyntheticchemistry.Thetextbookmaintainsatraditionalandlogicalapproachindetailingcarbon--carbonbondformations,followedbyanewchapteronthefunctionalizationofalkenesandconcludingwithoxidationandreductionreactions.Referencestylehasbeenimprovedtoincludefootnotes,allowingeasyandrapidaccesstotheprimaryliterature.Inaddition,aselectionofproblemshasbeenaddedattheendofeachchapter,withanswersattheendofthebook.Thebookwillbeofsignificantinteresttochemistryandbiochemistrystudentsatadvancedundergraduateandgraduatelevel,aswellastoresearchersinacademiaandindustrywhowishtofamiliarizethemselveswithmodemsyntheticmethods.

【目录】

Prefacetothefirstedition
Prefacetothefourthedition
1Formationofcarbon-carbonsinglebonds
1.1Main-groupchemistry
1.1.1Alkylationofenolatesandenamines
1.1.2Conjugateadditionreactionsofenolatesandenamines
1.1.3Thealdolreaction
1.1.4Asymmetricmethodologywithenolatesandenamines
1.1.50rganolithiumreagents
1.1.60rganomagnesiumreagents
1.1.7Organozincreagents
1.1.8Allylicorganometallicsofboron，siliconandtin
1.2Transition-metalchemistry
Problems
1.2.1Organocopperreagents
1.2.2Organochromiumchemistry
1.2.3Organocobaltchemistry
1.2.40rganopalladiumchemistry

2Formationofcarbon-carbondoublebonds
2.1[3-Eliminationreactions
2.2Pyrolyticsyneliminations
2.3Fragmentationreactions
2.4Alkenesfromhydrazones
2.5Alkenesfrom1，2-diols
2.6Alkenesfromalkynes
2.7TheWittigandrelatedreactions
2.8Alkenesfromsulfones
2.9Alkenesusingtitaniumorchromiumreagents
2.10Alkenemetathesisreactions
Problems

3Pericyclicreactions
3.1TheDiels-Aldercycloadditionreaction
3.1.1Thedienophile
3.1.2Thediene
3.1.3RegiochemistryoftheDiels-Alderreaction
3.1.4StereochemistryoftheDiels-Alderreaction
3.1.5IntramolecularDiels-Alderreactions
3.1.6TheretroDiels-Alderreaction
3.1.7AsymmetricDiels-Alderreactions
3.2[2+2]Cycloadditionreactions
3.3Cycloadditionreactionswithallylcationsandallylanions
3.41，3-Dipolarcycloadditionreactions
3.5Theenereaction
3.6[3，3]-Sigmatropicrearrangements
3.6.1TheCoperearrangement
3.6.2TheClaisenrearrangement
3.7[2，3]-Sigmatropicrearrangements
3.8Electrocyclicreactions
Problems

4Radicalandcarbenechemistry
4.1Radicals
4.1.1Radicalabstractionreactions
4.1.2Radicaladditionreactions
4.2Carbenes
Problems
Functionalizationofalkenes
5.1Hydroboration
5.1.1Reactionsoforganoboranes
5.2Epoxidationandaziridination
5.2.1Epoxidation
5.2.2Asymmetricepoxidation
5.2.3Aziridination
5.3Dihydroxylation
5.3.1Dihydroxylationwithosmiumtetroxide
5.3.2Othermethodsofdihydroxylation
5.3.3Amino-hydroxylation
5.4Oxidativecleavage
5.5Palladium-catalysedoxidationofaikenes
Problems

6Oxidation
6.1Oxidationofhydrocarbons
6.1.1Alkanes
6.1.2Aromatichydrocarbons
6.1.3Alkenes
6.2Oxidationofalcohols
6.2.1Chromiumreagents
6.2.2Oxidationviaalkoxysulfoniumsalts
6.2.3Manganesereagents
6.2.4Othermetal-basedoxidants
6.2.5Othernon-metal-basedoxidants
6.2.6oxidationtocarboxylicacidsoresters
6.3Oxidationofketones
6.3.1a，~~3-Unsaturatedketones
6.3.2a-Hydroxy-ketones
6.3.3Baeyer-Villigeroxidationofketones
Problems

7Reduction
7.1Catalytichydrogenation
7.2Reductionbydissolvingmetals
7.3Reductionbyhydride-transferreagents
7.3.3Derivativesoflithiumaluminiumhydrideandsodium
borohydride
7.3.4Mixedlithiumaluminiumhydride-aluminiumchloride
reagents
7.3.5Diisobutylaluminiumhydride(DIBAL-H)
7.3.6Sodiumcyanoborohydrideandsodium
triacetoxyborohydride
7.3.7Boraneandderivatives
7.4Othermethodsofreduction
7.4.1Enzymecatalysed
7.4.2Wolff-Kishnerreduction
7.4.3Reductionswithdiimide
7.4.4Reductionswithtrialkylsilanes
Problems
Answerstoproblems
Index